Study of Apolipoprotein E Polymorphism in Normal Healthy Controls from Northern India

Study of Apolipoprotein E Polymorphism in Normal Healthy Controls from Northern India

S. Chhabraa, D.P. Agarwalb, S. Vasishtc, K. Luthraa, R. Narangc, S.C. Manchandac, L.M. Srivastavad and N. Dasa,∗ Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India Institute of Human Genetics, University of Hamburg, Germany Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India Department of Biochemistry, Sir Ganga Ram Hospital, Ne...

Apolipoprotein E polymorphism and dementia: a hospital-based study from southern India.

BACKGROUND/AIMS To evaluate the ApoE gene polymorphism among patients with dementia from southern India. METHODS Persons with dementia attending a geriatric clinic in a hospital setting located in southern India and matched controls were recruited. All subjects were evaluated on standard assessments and were diagnosed according to the ICD-10; genotyping was done at the apolipoprotein E (ApoE)...

Apolipoprotein E Polymorphism in an Iranian Hypercholestrolemic Population

Apolipoprotein E (apo E) is a structural constituent of several serum lipoprotein classes. It plays an important role in lipid metabolism by acting as a ligand for low-density lipoprotein (LDL) and chylomicron remnant receptors. Three common alleles called e2, e3 and e4 have been described, which code for three protein isoforms (E2, E3 and E4). The polymorphism is clinically significant, and it...

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis

The Distribution of Apolipoprotein E Gene Polymorphism and Apolipoprotein E Levels among Coronary Artery Patients Compared to Controls.

OBJECTIVE Coronary artery disease (CAD) is a multifactorial disease that is caused by various genetics and environmental factors. Genetically, predisposition is an important component for CAD. The candidate apolipoprotein E (apoE) gene is the most studied one. ApoE is composed of e2, e3, e4 alleles and E2/2, E2/3, E2/4, E3/3, E3/4, E4/4 genotypes. In this study, the relationship between CAD and...